Sunday, December 21, 2008
Medication, dependence and addiction
Posted by Unknown at 12:31 PM 1 comments
Labels: medications
Why I Hate MSG (from the Experience Project
But worse, MSG also causes respiratory distress. For me it sometimes causes numbness of the lips and tongue. I used to be on asthma medication before I discovered that MSG could cause respiratory distress. When I started being careful to check for MSG on the food ingredient lists, I was able to stop taking asthma medication. However, MSG may be in the "spices" or "flavorings" in certain products. It is (astoundingly) considered a GRAS (generally regarded as safe) food additive.
Studies show that just two tablespoons of MSG can cause seizures in dogs . And since MSG was introduced as a common food additive in 1948, cases of autism and ADHD have risen sharply.
Posted by Unknown at 12:19 PM 1 comments
Labels: food additives, monosodium glutamate
Saturday, December 13, 2008
I love the night shift
Mobile post sent by lilystrange using Utterli. Replies.
Posted by Unknown at 10:46 PM 0 comments
Friday, December 12, 2008
The Flu Shot and Anti-viral medications
Posted by Unknown at 11:18 PM 0 comments
Labels: medications, viruses
Wednesday, November 05, 2008
Urinary Incontinence
Here are the results of an exciting quiz that I took at everydayhealth.com
High risk.
Your responses indicate that you have significant difficulty controlling your bladder, and therefore you are probably experiencing an overactive bladder or some other problem with incontinence. You should make an appointment to discuss your symptoms and concerns with your doctor as soon as possible.
An overactive bladder is characterized by a recurring, strong, and sudden need to urinate. A person with an overactive bladder tends to urinate eight to ten or more times a day, and is also likely to experience leakage in between. The urgent need to urinate, also known as urge incontinence, is a major symptom of an overactive bladder.
This type of incontinence is most common among elderly people, but it’s not a normal part of the aging process, as many mistakenly believe; urge incontinence is caused by other conditions or disorders. The National Institute on Aging reports that it commonly occurs as a result of diabetes, stroke, Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis, and that it can sometimes be an early sign of bladder cancer.
There are three other types of incontinence that might possibly be contributing to your symptoms.
* Stress incontinence: Stress on the lower stomach muscles causes urine leakage. This is most common among younger and middle-aged women.
* Overflow incontinence: An overfilled bladder causes a constant dripping of urine. This can occur, for example, when an enlarged prostate blocks a man’s urethra.
* Functional incontinence: The normal ability to control urination is compromised by an inability to get to the bathroom quickly enough.
In general, women are more likely than men to experience urinary incontinence, mainly as a result of childbirth complications, medical treatment, trauma, and changes that occur in the body with the onset of menopause. But there are many medical problems that can cause incontinence, including weakened or overactive pelvic muscles; bladder nerve damage; limited mobility; urinary tract, kidney, and bladder infections; diabetes; and high calcium levels.
Lifestyle problems, such as obesity, poor eating habits, and smoking can also contribute to incontinence. Obesity has been linked to urinary difficulties in both men and women, but studies show that women with a high body mass index (a BMI of 30 or higher) are more likely to experience stress incontinence. Avoiding bladder irritants, such as citrus and spicy foods, as well as anything sweetened with aspartame (NutraSweet), carbonated drinks, and diuretics such as caffeine and alcohol can make a difference. Quitting or cutting down on smoking may also reduce symptoms of stress incontinence, since female smokers are twice as likely as nonsmokers to develop this type of incontinence.
Additionally, keep in mind that certain medications and pelvic or abdominal surgeries can also cause incontinence, so be sure to discuss any risks as well as possible alternatives with your doctor.
These days, many options are available for treating incontinence, and the treatments are improving all the time. Even if your attempts to solve your incontinence problems were unsuccessful in the past, the health care community’s management of incontinence, including the methods of diagnosis and treatment, has greatly improved in recent years. You don’t have to suffer from the inconveniences and discomforts associated with an overactive bladder or incontinence. You’ve already taken the first step by taking this quiz and starting to educate yourself about incontinence. Next, make an appointment with your doctor, and start down the road to recovery!
My comments: Yes, I do have some issues with urinary incontinence. I am not elderly yet. And I'm not going to take the medications for it. The side effects are worse than the problem. Nor am I going to get that procedure where they inject silicone into the urethra. Are you fucking kidding me? Nobody is sticking a needle in there!
I think I developed this problem mostly due to my tendency to hold my pee for long periods of time when I was younger because of the types of jobs I worked. It would sometimes be a couple of hours beyond when I felt the urge before I would get to the bathroom. When I was in my late 30's it became harder and harder to hold it and by the time I was 40, I had sprung a leak. I use Poise-type pads. For me it seems better than the alternatives!
Posted by Unknown at 11:34 AM 1 comments
Labels: incontinence, urinary system
Tuesday, August 12, 2008
Dangerous Drugs according to Docs
8 Drugs Doctors Would Never Take
If they won't use these medications, why should you?
By Morgan Lord, Men's Health
Prescription For Danger?
With 3,480 pages of fine print, the Physicians' Desk Reference (a.k.a. PDR) is not a quick read. That's because it contains every iota of information on more than 4,000 prescription medications. Heck, the PDR is medication — a humongous sleeping pill.
Doctors count on this compendium to help them make smart prescribing decisions — in other words, to choose drugs that will solve their patients' medical problems without creating new ones. Unfortunately, it seems some doctors rarely pull the PDR off the shelf. Or if they do crack it open, they don't stay versed on emerging research that may suddenly make a once-trusted treatment one to avoid. Worst case: You swallow something that has no business being inside your body.
Of course, plenty of M.D.'s do know which prescription and over-the-counter drugs are duds, dangers, or both. So we asked them, "Which medications would you skip?" Their list is your second opinion. If you're on any of these meds, talk to your doctor. Maybe he or she will finally open that big red book with all the dust on it.
Advair
It's asthma medicine... that could make your asthma deadly. Advair contains the long-acting beta-agonist (LABA) salmeterol. A 2006 analysis of 19 trials, published in the Annals of Internal Medicine, found that regular use of LABAs can increase the severity of an asthma attack. Because salmeterol is more widely prescribed than other LABAs, the danger is greater — the researchers estimate that salmeterol may contribute to as many as 5,000 asthma-related deaths in the United States each year. In 2006, similarly disturbing findings from an earlier salmeterol study prompted the FDA to tag Advair with a "black box" warning — the agency's highest caution level.
Your New Strategy
No matter what you may have heard, a LABA, such as the one in Advair, is not the only option, says Philip Rodgers, Pharm.D., a clinical associate professor at the University of North Carolina school of pharmacy. For instance, if you have mild asthma, an inhaled corticosteroid such as Flovent is often all you need. Still wheezing? "Patients can also consider an inhaled corticosteroid paired with a leukotriene modifier," says Dr. Rodgers. This combo won't create dangerous inflammation, and according to a Scottish review, it's as effective as a corticosteroid-and-LABA combo.
Avandia
Diabetes is destructive enough on its own, but if you try to control it with rosiglitazone — better known by the brand name Avandia — you could be headed for a heart attack. Last September, a Journal of the American Medical Association (JAMA) study found that people who took rosiglitazone for at least a year increased their risk of heart failure or a heart attack by 109 percent and 42 percent, respectively, compared with those who took other oral diabetes medications or a placebo.
The reason? While there have been some reports that Avandia use may cause dangerous fluid retention or raise artery-clogging LDL cholesterol, no one is sure if these are the culprits. That's because the results of similar large studies have been mixed. So the FDA has asked GlaxoSmithKline, the maker of Avandia, to conduct a new long-term study assessing users' heart risks. There's only one problem: The study isn't expected to start until later this year.
Your New Strategy
Stick with a proven performer. "I prefer metformin, an older, cheaper, more dependable medication," says Sonal Singh, M.D., the lead author of the JAMAstudy. "Avandia is now a last resort." Dr. Singh recommends that you talk to your doctor about cholesterol-lowering medicines, such as statins or the B vitamin niacin. Swallowing high doses (1,000 milligrams) of niacin daily may raise your HDL (good) cholesterol by as much as 24 percent, while at the same time lowering your LDL and triglyceride levels.
Celebrex
Once nicknamed "super aspirin," Celebrex is now better known for its side effects than for its pain-relieving prowess. The drug has been linked to increased risks of stomach bleeding, kidney trouble, and liver damage. But according to a 2005 New England Journal of Medicine study, the biggest threat is to your heart: People taking 200 mg of Celebrex twice a day more than doubled their risk of dying of cardiovascular disease. Those on 400 mg twice a day more than tripled their risk, compared with people taking a placebo.
And yet Celebrex, a COX-2 inhibitor, is still available, even though two other drugs of that class, Bextra and Vioxx, were pulled off the market due to a similar risk of heart damage. The caveat to the consumer? In 2004, the FDA advised doctors to consider alternatives to Celebrex.
Your New Strategy
What you don't want to do is stop swallowing Celebrex and begin knocking back ibuprofen, because regular use of high doses of nonsteroidal anti-inflammatory drugs (NSAIDs) can lead to gastrointestinal bleeding. A safer swap is acupuncture. A German study found that for people suffering from chronic lower-back pain, twice-weekly acupuncture sessions were twice as effective as conventional treatments with drugs, physical therapy, and exercise. The strategic needling may stimulate central-nervous-system pathways to release the body's own painkillers, including endorphins and enkephalins, says Duke University anesthesiologist Tong-Joo Gan, M.D. You can find a certified acupuncturist in your area at medicalacupuncture.org/findadoc/index.html.
CONTINUED: More input for your second opinion.
Ketek
Most bacteria in the lungs and sinuses don't stand a chance against Ketek, but you might not either. This antibiotic, which has traditionally been prescribed for respiratory-tract infections, carries a higher risk of severe liver side effects than similar antibiotics do. "Ketek can cause heart-rhythm problems, can lead to liver disease, and could interact poorly with other medications you may be taking," says Dr. Rodgers. "Unfortunately, it's still available, and although many doctors are aware of the risks, some may still prescribe it without caution." In February 2007, the FDA limited the usage of Ketek to the treatment of pneumonia.
Your New Strategy
Can't imagine catching pneumonia? The last time the Centers for Disease Control and Prevention calculated the top 10 killers of men, this deadly lung infection (along with the flu) came in seventh. Avoid backing yourself into a corner where you might need Ketek by always signing up for your annual flu shot — if you have pneumonia, it'll reduce your risk of dying of the infection by 40 percent. And if you still end up staring at a scrip for Ketek, Dr. Rodgers recommends asking to be treated with one of several safer alternatives, such as Augmentin or the antibiotics doxycycline or Zithromax.
Prilosec and Nexium
Heartburn can be uncomfortable, but heart attacks can be fatal, which is why the FDA has investigated a suspected link between cardiac trouble and the acid-reflux remedies Prilosec and Nexium. In December 2007, the agency concluded that there was no "likely" connection. Translation: The scientific jury is still out. In the meantime, there are other reasons to be concerned. Because Prilosec and Nexium are proton-pump inhibitors, they are both incredibly effective at stopping acid production in the stomach — perhaps too effective.
A lack of acid may raise your risk of pneumonia, because the same stuff that makes your chest feel as if it's burning also kills incoming bacteria and viruses. You may also have an elevated risk of bone loss — in the less acidic environment, certain forms of calcium may not be absorbed effectively during digestion. "The risk of a fracture has been estimated to be over 40 percent higher in patients who use these drugs long-term, and the risk clearly increases with duration of therapy," says Dr. Rodgers.
Your New Strategy
When you feel the fire, first try to extinguish it with Zantac 150 or Pepcid AC. Both of these OTC products work by blocking histamine from stimulating the stomach cells that produce acid. Just know that neither drug is a long-term fix.
"To really cure the problem, lose weight," says Michael Roizen, M.D., chief wellness officer at the Cleveland Clinic and coauthor of YOU: The Owner's Manual. That's because when you're overweight, excess belly fat puts pressure on and changes the angle of your esophagus, pulling open the valve that's supposed to prevent stomach-acid leaks. This in turn makes it easier for that burning sensation to travel up into your chest.
Visine Original
What possible harm to your peepers could come from these seemingly innocuous eyedrops? "Visine gets the red out, but it does so by shrinking blood vessels, just like Afrin shrinks the vessels in your nose," says Thomas Steinemann, M.D., a spokesman for the American Academy of Ophthalmology. Overuse of the active ingredient tetrahydrozoline can perpetuate the vessel dilating-and-constricting cycle and may cause even more redness.
Your New Strategy
If you still want to rely on Visine, at least make sure you don't use too many drops per dose and you don't use the stuff for more than 3 or 4 days. But you'd really be better off figuring out the underlying cause of the redness and treating that instead. If it's dryness, use preservative-free artificial tears, recommends Dr. Steinemann. Visine Pure Tears Portables is a good choice for moisture minus side effects. On the other hand, if your eyes are itchy and red because of allergies, pick up OTC antiallergy drops, such as Zaditor. It contains an antihistamine to interrupt the allergic response but no vasoconstrictor to cause rebound redness.
Pseudoephedrine
Forget that this decongestant can be turned into methamphetamine. People with heart disease or hypertension should watch out for any legitimate drug that contains pseudoephedrine. See, pseudoephedrine doesn't just constrict the blood vessels in your nose and sinuses; it can also raise blood pressure and heart rate, setting the stage for vascular catastrophe. Over the years, pseudoephedrine has been linked to heart attacks and strokes. "Pseudoephedrine can also worsen symptoms of benign prostate disease and glaucoma," says Dr. Rodgers.
Your New Strategy
Other OTC oral nasal decongestants can contain phenylephrine, which has a safety profile similar to pseudoephedrine's. A 2007 review didn't find enough evidence that phenylephrine was effective. Our advice: Avoid meds altogether and clear your nasal passages with a neti pot, the strangely named system that allows you to flush your sinuses with saline ($15, sinucleanse.com). University of Wisconsin researchers found that people who used a neti pot felt their congestion and head pain improve by as much as 57 percent. Granted, the flushing sensation is odd at first, but give it a chance. Dr. Roizen did: "I do it every day after I brush my teeth," he says.
More About Medications on MSN Health & Fitness
Are Generic Drugs Safe?
Rx for Safety
The Health Mistake Too Many Americans Make
Posted by Cie Cheesemeister at 1:49 AM 1 comments
Labels: medication safety, medications, pharmaceutical safety, pharmaceuticals
Wednesday, June 11, 2008
The Cheese Is In The House
Posted by Cie Cheesemeister at 12:17 AM 0 comments
Labels: dopey diversions, medical shows, memes
Saturday, May 10, 2008
IBS = Fun (NOT!!!!)
Warning: graphic, crude, visceral humor as a way with coping with a messy and painful condition.
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This has, comparatively, been less bad than some occasions when the pain was bad enough to rival labor cramps, but still, no picnic. There have been a couple times when the pain was so bad I thought about going to the ER. This time I just have a hot abdomen, some painful cramps although not knock-me-over painful, and the inconvenience of having to go to the can every 15 minutes.
How do I know its IBS and not just something I ate?
The bowel movements with IBS, at least in my case, are often normal consistency, they are just too frequent, and there are accompanying abdominal cramps. I sometimes have constipation, sometimes diarrhea. But whatever the case, this shit sucks. I guess I just have to count my blessings that a bad bout generally only happens about once a month. Some people have to face the horror daily.
Posted by Unknown at 2:21 AM 5 comments
Labels: IBS
Saturday, April 26, 2008
Blood Pressure
I'm going to monitor my blood pressure daily for the next week and make an appointment with the doctor. My current doctor is pretty conservative about prescribing medications so if he thinks I should try a blood pressure med, I will. My mother, unfortunately, has had a terrible time with side effects from blood pressure meds. I tend to be pretty intolerant of most meds as a rule, so it could be a challenge.
I used to take Inderal for hand tremors but then discovered that the tremors only happened around the time of my period, so I stopped. The only side effect was that it made me tired, but I'm tired all the time anyway. I'll take it again if I have to. It's better than developing atherosclerosis, which also happened to my father, who had untreated high blood pressure and ended up having a hemorrhagic stroke 4 years ago. I've been having more heart palpitations recently and it's kinda worrying me.
Posted by Unknown at 5:12 PM 1 comments
Labels: atherosclerosis, heart palpitations, hemorrhagic stroke, high blood pressure, Inderal, stroke
Friday, April 04, 2008
My Apology
To the Residents in My Care
Though you never see me grumble to your face, I do it behind your back before I come into your room when you need something. It isn't you personally. It's just that I'm tired all the time and never get enough rest. This position is so easy compared to what I used to do that I really don't have the right to be grumbling but to be honest I'd rather be napping or writing or playing computer games than taking care of you. Sorry I'm such an asshole. I actually do care about what happens to you. I'm just old before my time and crusty inside.
Posted by Unknown at 5:27 AM 0 comments
Labels: caregiver burnout, Joe Apology
Tuesday, March 11, 2008
Ear Wax
The cure?
Alpha Lipoic Acid.
My mother read about this recently. She told me and I thought it was worth a try. Most of these "miracle cures" are half-assed at best and really costly, but this literally worked within five days. I still get ear wax (we do need some) but it's drier, far less copious, and way more manageable.
Alpha Lipoic Acid is a simple antioxidant. It costs around $10 for 100 capsules and is available in any natural food store. I'm not being comped in any way for saying this. I use the Now brand, which is usually the least expensive of the natural supplements brands. I just wanted to let anyone else who might be troubled by excess ear wax know that there is a possible, very inexpensive solution that may work for you too!
Posted by Cie Cheesemeister at 10:48 PM 2 comments
Labels: Alpha Lipoic Acid, ear wax
Monday, March 10, 2008
Aides and Techs
My grandmother had an 8th grade education because she had to go to work early on. She always thought that she was stupid. She wasn't. She worked as an orderly in a mental hospital until she was forced to retire at age 65, and she actually liked working with the patients. She knew more about them than the psychiatrists did. It's sad how society de-values people in essential positions like this.
Posted by Unknown at 10:49 PM 0 comments
Labels: caregivers
Tuesday, March 04, 2008
Caregiver Stress
My mother is basically quite healthy, other than having had a hip replacement a year and a half ago and cataract surgery six months ago. But my father has a lot of needs and has always been sort of a "high maintenance" individual.
Here is the article.
Sick Spouse Shortens One's Life
Having a spouse or partner who suffers from debilitating illness raises one's own risk of premature death, a new study finds. The study, conducted by Harvard Medical School researchers, was recently published in the New England Journal of Medicine. Researchers studied medical records from more than 500,000 elderly couples, tracking the health status of both partners over the course of nine years. According to the results of their study, researchers concluded that the phenomenon known as the "bereavement effect" or "caregiver burden" appears to be grounded in statistics. Men and women with sick spouses were up to five times more likely than their peers to die from a variety of causes, including suicide, accidents, infections and undiagnosed conditions.
Posted by Unknown at 4:53 PM 2 comments
Labels: caregiving
Monday, March 03, 2008
"Aging In Place"
Posted by Cie Cheesemeister at 11:58 PM 2 comments
Labels: work frustrations
Breast Cancer Patient Protection Act
From a nurse:
I'll never forget the look in my patients eyes when I had to tell them they had to go home with the drains, new exercises and no breast.
I remember begging the Doctors to keep these women in the hospital longer, only to hear that they would, but their hands were tied by the insurance companies.
So there I sat with my patients, giving them the instructions they needed to take care of themselves, knowing full well they didn't grasp half of what I was saying, because the glazed, hopeless, frightened look spoke louder than the quiet 'Thank You' they muttered.
A mastectomy is when a woman's breast is removed in order to remove cancerous breast cells/tissue.
If you know anyone who has had a Mastectomy, you may know that there is a lot of discomfort and pain afterwards.
Insurance companies are trying to make mastectomies an outpatient procedure.
Let's give women the chance to recover properly in the hospital for 2 days after surgery.
It takes 2 seconds to do this and is very important .. Please take the time and do it really quick!
Please send this to everyone in your address book.
If there was ever a time when our voices and choices should be heard, this is one of those times.
If you're receiving this, it's because I think you will take the 30 seconds to go to vote on this issue and send it on to others.
You know who will do the same.
There's a bill called the Breast Cancer Patient Protection Act which will require Insurance Companies to cover a minimum 48-hour hospital stay for patients undergoing a mastectomy. It's about eliminating the 'drive-through mastectomy' where women are forced to go home just a
few hours after surgery, against the wishes of their doctor, still groggy from anesthesia and sometimes with drainage tubes still attached.
Lifetime Television has put this bill on their Web page with a petition drive to show your support. Last year over half the House signed on.
PLEASE!! Sign the petition by clicking on the Web site below. You need not give more than your name and zip code number.
http://www.lifetimetv.com/breastcancer/petition/signpetition.php
This takes about 2 seconds.
PLEASE PASS THIS ON to your friends and family, and on behalf of all women, THANKS!!! :-)
Posted by Unknown at 5:25 AM 1 comments
Labels: breast cancer, patient rights
Monday, February 25, 2008
There isn't always a positive outcome
My father gets the Stroke Connection magazine and he feels about it's approach the way you felt about the t-shirt. Not everyone survives cancer, and not everyone who has a stroke makes a full recovery and is able to go back to a productive life. While giving hope these organizations should also not be forgetting about the reality, about the people grieving the loved ones lost to cancer, about people grieving the functions lost to stroke.
Posted by Cie Cheesemeister at 12:51 AM 0 comments
Labels: American Cancer Society, American Heart Association, cancer, medical literature, stroke
Sunday, February 24, 2008
Hemorrhages on the Sclera
Posted by Unknown at 2:32 AM 0 comments
Labels: bloodshot eyes, exhaustion, eyes, hemorrhaged sclera, stress
Wednesday, February 20, 2008
The Chubby Curmudgeon Strikes Back
I am a 43 year old person who has, sadly, put on quite a bit of weight over the last 15 years, in part due to admittedly less than perfect eating habits, in part due to medication and health conditions such as hypothyroidism and polycystic ovarian syndrome. However, I am no less healthy than my slimmer co-workers. I have only called in sick twice in the past three years. I had to go to the emergency room once a little over a year ago--for ear wax that was pressing against the ear drum and caused me vertigo and also a frightening blood pressure spike. Hypertension runs in my family, but it doesn't seem to have anything to do with weight. My brother, who is now 39, had to start taking blood pressure medication in his early 30's, and he is not overweight. My blood pressure is on the borderline and I'm watching it. But I still don't have to take medication for it yet. The medications I take are lithium for bipolar disorder (which does cause weight gain) and thyroid medication. I am also fairly active, so the myth that all heavy people do is sit around eating is just that--a myth. Most of the big people I have known have been hard-working folk. Rather than engaging in prejudiced behavior against one segment of the population, let us try to find a solution that works for everybody.
Posted by Cie Cheesemeister at 5:22 AM 0 comments
Labels: prejudice, weight issues
Saturday, February 16, 2008
Terrible and Funny Tales From The E.R.
Posted by Cie Cheesemeister at 5:00 PM 0 comments
Labels: medical anecdotes
Tuesday, February 12, 2008
How Low Can You Go?
Does it get any lower than stealing from the poor and the elderly?
Why would anyone do that?
In another incident, a woman had been "working" retirement communities in the area. Our building is locked at night but during the day it is open. This woman came in, knocked on one of the residents' doors and pretended she was looking for someone, asking the resident if she could help. The perpetrator then said she was thirsty and asked for a glass of water. While the resident was getting the water, the woman stole her purse. She then proceeded to chat with the resident for a few more minutes before leaving. A few days later there were reports in the paper of similar incidents at other retirement homes.
None of this helped calm the unfortunate victim of this unsettling crime, who was an Austrian immigrant that had lived through the horrors of World War II. Her cognitive abilities were declining and that in itself was causing severe anxiety. The night after the incident she called me to her apartment. I talked to her for 20 minutes in an attempt to calm her but I fear I wasn't able to do much good. Then her abilities to care for herself at all began to decline. I'll never be sure how much of this was psychosomatic. She ended up in the hospital and from there was transferred to our facility's health care center. She never returned to her apartment, dying in the health care center a few months later. She completely shut down emotionally and her physical faculties followed.
Granted, "Gwenda's" short term memory was beginning to fail her, but before this incident she would walk around the building twice a day for exercise and every morning before I went home she would be there at the office for her medicines with a cheery "Gud Mornink, how are you?" After she was victimized, she became a terrified shell of herself. While she didn't say so, I'm sure that the invasion of her home brought back memories of a frightening time in her existence, perhaps some that she had repressed for years. Her drastic decline following her victimization was shocking and, I think, completely unnecessary.
Shame on those who victimize the most vulnerable so callously! But due to the fact that they have no conscience, I suppose that they feel no shame.
Posted by Cie Cheesemeister at 6:52 PM 0 comments
Labels: con artists, vulnerable victims
Sunday, February 03, 2008
Virus Du Jour
At this point I'm trying not to cough because it will only cause worse irritation to the tissues in my throat and unwanted choking sensations. At this point the cough is semi-productive although there isn't any discomfort in my lungs, i.e. bronchitis. So far I'm pretty sure this is a virus and not strep. My throat isn't that sore and I'm not running a fever.
If you find yourself having to cough constantly, particularly an explosive dry cough, do what I should have done and nip it in the bud with some cough syrup so your throat doesn't end up as irritated as I let mine become. Normally I let minor cold and cough run their course, but I would have been advised to stop this one. Now I need to allow my throat to heal and deal with the unsettling gagging sensations that come with having irritating the tissue with so much coughing.
Posted by Cie Cheesemeister at 3:57 AM 1 comments
Labels: Calms Forte, colds, coughing, Hyland's, Kava, laryngospasm, panic attacks, pneumonia, strep, viruses
Thursday, January 31, 2008
Genetic mutation stuff--eyes
Genetic mutation makes those brown eyes blue
Scientists find that blue-eyed individuals have a single, common ancestor
Carolyn Kaster / AP file
By Jeanna Bryner
updated 12:01 p.m. MT, Thurs., Jan. 31, 2008
How did actress Reese Witherspoon get those big blue eyes? A team of scientists has found that blue eyes are linked to a genetic mutation that occurred between 6,000 and 10,000 years ago.
People with blue eyes have a single, common ancestor, according to new research.
A team of scientists has tracked down a genetic mutation that leads to blue eyes. The mutation occurred between 6,000 and 10,000 years ago, so before then, there were no blue eyes.
"Originally, we all had brown eyes," said Hans Eiberg from the Department of Cellular and Molecular Medicine at the University of Copenhagen.
The mutation affected the so-called OCA2 gene, which is involved in the production of melanin, the pigment that gives color to our hair, eyes and skin.
"A genetic mutation affecting the OCA2 gene in our chromosomes resulted in the creation of a 'switch,' which literally 'turned off' the ability to produce brown eyes," Eiberg said.
The genetic switch is located in the gene adjacent to OCA2 and rather than completely turning off the gene, the switch limits its action, which reduces the production of melanin in the iris. In effect, the turned-down switch diluted brown eyes to blue.
If the OCA2 gene had been completely shut down, our hair, eyes and skin would be melanin-less, a condition known as albinism.
"It's exactly what I sort of expected to see from what we know about selection around this area," said John Hawks of the University of Wisconsin-Madison, referring to the study results regarding the OCA2 gene. Hawks was not involved in the current study.
Baby blues
Eiberg and his team examined DNA from mitochondria, the cells' energy-making structures, of blue-eyed individuals in countries including Jordan, Denmark and Turkey. This genetic material comes from females, so it can trace maternal lineages.
They specifically looked at sequences of DNA on the OCA2 gene and the genetic mutation associated with turning down melanin production.
Over the course of several generations, segments of ancestral DNA get shuffled so that individuals have varying sequences. Some of these segments, however, that haven't been reshuffled are called haplotypes. If a group of individuals shares long haplotypes, that means the sequence arose relatively recently in our human ancestors. The DNA sequence didn't have enough time to get mixed up.
"What they were able to show is that the people who have blue eyes in Denmark, as far as Jordan, these people all have this same haplotype, they all have exactly the same gene changes that are all linked to this one mutation that makes eyes blue," Hawks said in a telephone interview.
Melanin switch
The mutation is what regulates the OCA2 switch for melanin production. And depending on the amount of melanin in the iris, a person can end up with eye color ranging from brown to green. Brown-eyed individuals have considerable individual variation in the area of their DNA that controls melanin production. But they found that blue-eyed individuals only have a small degree of variation in the amount of melanin in their eyes.
"Out of 800 persons we have only found one person which didn't fit — but his eye color was blue with a single brown spot," Eiberg told LiveScience, referring to the finding that blue-eyed individuals all had the same sequence of DNA linked with melanin production.
"From this we can conclude that all blue-eyed individuals are linked to the same ancestor," Eiberg said. "They have all inherited the same switch at exactly the same spot in their DNA." Eiberg and his colleagues detailed their study in the Jan. 3 online edition of the journal Human Genetics.
That genetic switch somehow spread throughout Europe and now other parts of the world.
"The question really is, 'Why did we go from having nobody on Earth with blue eyes 10,000 years ago to having 20 or 40 percent of Europeans having blue eyes now?" Hawks said. "This gene does something good for people. It makes them have more kids."
Posted by Cie Cheesemeister at 10:32 PM 0 comments
Labels: genetics
Wednesday, January 30, 2008
New Changes
Posted by Unknown at 5:01 PM 0 comments
Labels: blog mergers